NeoProteomics

Expertise. Innovation. Results.

Publications

  1. Kaur, P., Kiselar, J.G., Shi, W., Yang, S., Chance, M.R. “Covalent Labeling Techniques for Characterizing Higher Order Structure of Monoclonal Antibodies”, in State of the Art and Emerging Technologies for Therapeutic Monoclonal Antibody Characterization. Volume 3. Defining the Next Generation of Analytical and Biophysical Techniques. Editors: Darryl Lee Davis, Oleg Borisov, and John Schiel, ACS Symposium Series # 1202, Chapter 3, pp 45- 73, (2015).
  2. Kaur P, Tomechko SE, Kiselar J, Shi W, Deperalta G, Wecksler AT, Gokulrangan G, Ling V, Chance MR. Characterizing monoclonal antibody structure by carboxyl group footprinting. MAbs (2015) 7(3):540-52. doi: 10.1080/19420862.2015.1023683. PMID: 25933350 PMCID: PMC4622658
  3. Kaur P, Kiselar J, Yang S, Chance MR. Quantitative protein topography analysis and high-resolution structure prediction using hydroxyl radical labeling and tandem-ion mass spectrometry (MS). Molecular & cellular proteomics : MCP. (2015);14(4):1159-68. doi:10.1074/mcp.O114.044362. PubMed PMID: 25687570; PubMed Central PMCID:PMC4390260.
  4. Huang W, Ravikumar KM, Chance MR, Yang S. “Quantitative mapping of protein structure by hydroxyl radical footprinting-mediated structural mass spectrometry: a protection factor analysis”. Biophys J (2015); 108(1):107-15. doi: 10.1016/j.bpj.2014.11.013. PMCID: PMC4286602
  5. Kaur, P.; Kiselar, J.; Shi, W.; Chance, M. R.; Covalent Labeling Techniques for Characterizing Higher Order Structure of Monoclonal Antibodies, Chapter 21, Current, State of the Art, and Emerging Technologies for the Analysis of Monoclonal Antibodies, ACS Books (2014)
  6. Kaur, P., Chance, M.R., Chapter 21: “The Utility of Mass Spectrometry Based Structural Proteomics in Biopharmaceutical Biologics Development”, Integrative Proteomics, ISBN 978-953- 51-0070-6, H-C Leung, Editor, In-Tech, p.395-412, (2012).
  7. Xu, G., Chance, M.R., Hydroxyl radical-mediated modification of proteins as probes for structural proteomics, Chem Rev. (2007) Aug;107(8):3514-43. PMID: 17683160 DOI: 10.1021/cr0682047
  8. Takamoto, K., Chance, M.R., Radiolytic protein footprinting with mass spectrometry to probe the structure of macromolecular complexes, Annu Rev Biophys Biomol Struct. (2006);35:251-76. DOI: 10.1146/annurev.biophys.35.040405.102050

 
Research Papers

 
The Utility of Mass Spectrometry Based Structural Proteomics in Biopharmaceutical Biologics Development
 
Poster Presentations

   
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