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Center for Synchrotron Biosciences

Many of the advances in structural molecular biology and related biosciences are the result of the rapidly occurring developments at synchrotrons. These include X-ray crystallography for protein structure determination, X-ray spectroscopy for examination of metalloprotein structure, and synchrotron footprinting technologies for examining macromolecular structure and dynamics. The Case School of Medicine of Case Western Reserve University established the Case Center for Proteomics and Bioinformatics for expanding the state-of-the art in proteomics research. This center provides administrative oversight for the Case Center for Synchrotron Biosciences (CSB) which is funded by the National Institute of Biomedical Imaging and Bioengineering (NIBIB) as a Biotechnology Research Resource to serve an international community of biomedical scientists. The CSB is catalyzing further development and application of synchrotron radiation tools through a number of multidisciplinary collaborations and partnerships among an international community of scientists. The research facility located at the Photon Sciences at the Brookhaven National Laboratory (BNL) in New York. Photon Sciences, as a Department of Energy funded facility, has as a mission to provide academic institutions access to synchrotron light through various collaboration and consortium arrangements.

$4.6 million from NIH puts CWRU Synchrotron lab on track to become No. 1 in world

Case Center for Synchrotron Biosciences assembles cutting-edge new beamlines at Brookhaven National Laboratory in Upton, N.Y. Case Western Reserve University's synchrotron facility at Brookhaven National Laboratory is on its way to becoming the No. 1 beamline facility for biology in the world by early 2016, thanks to a jumpstart grant of $4.6 million from the National Institute of Biomedical Imaging and Bioengineering (NIBIB), a component of the National Institutes of Health (NIH).

Diamond Detector Captures Last X-rays at NSLS;
It was a race to the end

On September 30, 2014, when the last photons came through the shutter at the National Synchrotron Light Source (NSLS) on its final day of operations, the new diamond detector at beamline X28C resolved the images with 1,000-pixel resolution.