NeoProteomics

Expertise. Innovation. Results.

YourCrosstalkerTM

In Fall of 2015, the YourCrosstalker systems biology analysis application will be launched. YourCrosstalker™ combines network analysis with pathway enrichment and a robust interactive visualization to provide a unique and powerful toolkit for systems biology analysis. The core YourCrosstalker™ algorithm uses a “seed” set of disease targets (found by GWAS, proteomic profiling, etc.) and a model of network crosstalk to search a global PPI for candidate sub-networks with a functional role in disease[1].

[1] Nibbe et al., An Integrative -omics Approach to Identify Functional Sub-Networks in Human Colorectal Cancer, Comput Biol 6(1): e1000639. doi:10.1371/journal.pcbi.1000639