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NeoProteomics, Inc. offers covalent labeling (CL) and mass spectrometry (MS) services to industry to characterize therapeutic proteins. CL-MS (often called protein footprinting) provides a high resolution and sensitive readout of the amino acid side chain enviornment for virtually all amino acids in a protein of interest.  Changes in solvent accessibility of amino acid side chains, due to ligand binding, sequence or process variation, or changes in formulation are easily read out by CL-MS technology and are immediately structurally intepretable.  Through this technology, NeoProteomics can assess your protein structure even for large antigens or antigens that are membrane proteins, or proteins with many disulfide bonds or multiple glycosylation sites.

Services Include:
Higher Order Structural Analysis
Epitope Mapping
Protein-Drug Interaction Mapping